Synthetic BiologybioRxivPreprint
Synergic homology directed recombination by PRDM9 meiotic factor
Marta Sanvicente-García, Lourdes González-Bermúdez, Isabel Turpín…·Avencia Sánchez-Mejías
This study enhances homology-directed repair (HDR) efficiency by using PRDM9-Cas9 fusion with CtIP, validated through reporter systems for small and longer edits.
DOI 10.1101/2022.12.05.519167