Author

Ryan M. Brown

University of Illinois ChicagoORCID 0000-0002-9577-4943Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ryan M. Brown1 paper · University of Virginia

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Donald J. Vander GriendiD· 2 shared Adriana DurakiiD· 1 shared Anthony J. WilliamsiD· 1 shared Audris BudreikaiD· 1 shared Carleen D. DeeganiD· 1 shared Charles S. Rogers· 1 shared Devin A. Schmeck· 1 shared Ella BoytimiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Donald J. Vander GriendORCID

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2 papers

Recent·Most cited

Vitamin D deficiency alters prostate epithelial differentiation and increases prostate cancer aggressiveness in ex vivo and in vivo models

Adriana Duraki, Kirsten D. Krieger, Sasha Celada, Robert A. Holt, Ryan M. Brown, Luyu Wang, Michael J. Schlicht, Maarten C. Bosland, Robert Michael Sargis, Donald J. Vander Griend, Larisa Nonn

This study shows vitamin D deficiency impairs prostate epithelial differentiation and promotes cancer aggressiveness in both ex vivo and in vivo models.

Cancer Letters · Jul 31, 2026Peer-reviewedCancer Biology

SOX2 utilizes FOXA1 as a heteromeric transcriptional partner to drive proliferation in therapy-resistant prostate cancer

John T. Phoenix, Audris Budreika, Devin A. Schmeck, Raymond J. Kostlan, Marina G. Ferrari, Kristen S. Young, Charles S. Rogers, Carleen D. Deegan, Marcus W. Bienko, Hannah E. Bergom, Ella Boytim, Ryan M. Brown, Julia A. Walewicz, Shreya K. Bhagi, Leigh Ellis, , Steven Kregel

This study identifies SOX2 and FOXA1 as a transcriptional partnership driving proliferation and lineage plasticity in therapy-resistant prostate cancer.

bioRxiv · Jul 18, 2025 · PreprintCancer Biology