Ella Boytim

This study develops novel oncolytic viruses derived from T1L mammalian orthoreovirus that enhance killing of therapy-resistant breast cancer stem-like cells.

The paper uses an organoid model to identify discrete transcriptional states and immune responses in colorectal cancer, revealing hidden evolutionary patterns and CMS transitions.

This study identifies SOX2 and FOXA1 as a transcriptional partnership driving proliferation and lineage plasticity in therapy-resistant prostate cancer.

This study uses multiomic analysis to investigate metabolic interactions between colorectal cancer cells and hepatocytes in liver metastasis, revealing metabolic shifts and potential therapeutic targets.

This paper introduces Local Leveling, a method to reduce bias in RNA-seq data, improving gene-gene relationship accuracy and statistical test results.