Author

Kristen S. Young

Loyola University ChicagoORCID 0000-0002-4159-623XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Sean William FanningiD· 3 shared Steven KregeliD· 3 shared Audris BudreikaiD· 2 shared Donald J. Vander GriendiD· 2 shared Govinda R HancockiD· 2 shared John T. PhoenixiD· 2 shared Marina G. FerrariiD· 2 shared Pushpinder BawaiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Sean William FanningORCID

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Author profile →

3 papers

Recent·Most cited

A non-enzymatic role for METTL3 as an Androgen Receptor co-regulator that promotes prostate cancer proliferation.

Raymond J. Kostlan, John T. Phoenix, Audris Budreika, Carli D. Deegan, Marina G. Ferrari, Elise T Warren, Pushpinder Bawa, Charles S Rogers, Divya Dureja, M Obaidulla Ibne Ali, Govinda R Hancock, Kristen S. Young, Gopal Gupta, Abhishek Solanki, Donald J. Vander Griend, , Steven Kregel

This study identifies METTL3 as a non-enzymatic AR co-regulator that promotes prostate cancer proliferation by supporting AR-driven transcriptional programs.

bioRxiv · Jul 9, 2026 · PreprintCancer Biology

SOX2 utilizes FOXA1 as a heteromeric transcriptional partner to drive proliferation in therapy-resistant prostate cancer

John T. Phoenix, Audris Budreika, Devin A. Schmeck, Raymond J. Kostlan, Marina G. Ferrari, Kristen S. Young, Charles S. Rogers, Carleen D. Deegan, Marcus W. Bienko, Hannah E. Bergom, Ella Boytim, Ryan M. Brown, Julia A. Walewicz, Shreya K. Bhagi, Leigh Ellis, , Steven Kregel

This study identifies SOX2 and FOXA1 as a transcriptional partnership driving proliferation and lineage plasticity in therapy-resistant prostate cancer.

bioRxiv · Jul 18, 2025 · PreprintCancer Biology

Targeting Unique Ligand Binding Domain Structural Features Downregulates DKK1 in Y537S ESR1 Mutant Breast Cancer Cells

Kristen S. Young, Govinda R Hancock, Emma C. Fink, Alexandra Zigrossi, Brenna Flowers, D. A. Cooper, Vy T. Nguyen, Millie Martinez, Khin Su Mon, Maarten C. Bosland, Donald R. Zak, Austin P Runde, Marina Nasrin Sharifi, Irida Kastrati, David D. L. Minh, , Sean William Fanning

This study investigates how a novel SERM, T6I-29, downregulates DKK1 in Y537S ESR1 mutant breast cancer cells and identifies DKK1 as a potential therapeutic target.

Breast Cancer Research · Jan 17, 2025Peer-reviewedCancer Biology