Maarten C. Bosland

Vitamin D deficiency alters prostate epithelial differentiation and increases prostate cancer aggressiveness in ex vivo and in vivo models

This study shows vitamin D deficiency impairs prostate epithelial differentiation and promotes cancer aggressiveness in both ex vivo and in vivo models.

In vivo investigation of STN1 downregulation in melanoma formation in adult mice following UV irradiation

The paper investigates the role of STN1 downregulation in UV-induced melanoma formation in mice, finding no significant effect on melanoma incidence in STN1-deficient mice.

Targeting Unique Ligand Binding Domain Structural Features Downregulates DKK1 in Y537S ESR1 Mutant Breast Cancer Cells

This study investigates how a novel SERM, T6I-29, downregulates DKK1 in Y537S ESR1 mutant breast cancer cells and identifies DKK1 as a potential therapeutic target.

DDX41 is needed for pre-and post-natal hematopoietic stem cell differentiation in mice

This study shows that DDX41 is essential for hematopoietic stem cell differentiation in mice, particularly affecting myeloid progenitor development and gene expression programs.