Author

Rajeev Dhupar

Atrium Health Wake Forest BaptistORCID 0000-0002-9581-3340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Adam C. SoloffiD· 2 shared Aatur Dilip SinghiiD· 1 shared Aditi KulkarniiD· 1 shared Angel Wang· 1 shared Armando P. SignoreiD· 1 shared Brian Robert IsettiD· 1 shared Carl Kim· 1 shared Carly ReederiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Adam C. SoloffORCID

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2 papers

Recent·Most cited

Integrative multi-omic analysis identifies tumor-intrinsic p38 as a driver of immune exclusion in human epithelial cancers

Rebekah Dadey, Krishna Beer Singh, Rose Doerfler, Riley Santiago, Brian Robert Isett, Christopher Deitrick, Carl Kim, Sarah Newman, Marion Joy, Katelyn Smith, Carly Reeder, Armando P. Signore, Ernest Michael Meyer, Tullia Carmela Bruno, Aditi Kulkarni, , Riyue Bao

This study identifies tumor-intrinsic p38 activation as a driver of immune exclusion in epithelial cancers and suggests it as a therapeutic target to overcome immunotherapy resistance.

bioRxiv · Jun 16, 2026 · PreprintCancer Biology

Microplastics inhibit macrophage bioenergetics impairing homeostatic function and immune responsiveness

Rajeev Dhupar, Hannah Mfonobong Udoh, Naila Noureen, Charles E. Bardawil, Xinyue Zhao, Mohsin Cheema, Shawna Tuli, Dylan Shields, Ksenia Mats, Omar Al-Bataineh, L Golla, Angel Wang, Ricardo Pineda, Melanie Koenigshoff, Shikhar Uttam, , Adam C. Soloff

This study shows that microplastics impair macrophage bioenergetics and immune function, reducing antigen presentation and increasing disease susceptibility.

bioRxiv · May 18, 2026 · PreprintImmunology