Author

Adam C. Soloff

University of PittsburghORCID 0000-0002-1467-8168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Rajeev DhupariD· 2 shared Rebekah DadeyiD· 2 shared Riyue BaoiD· 2 shared Aatur Dilip SinghiiD· 1 shared Aditi KulkarniiD· 1 shared Aidan R. ColeiD· 1 shared Akash KishoreiD· 1 shared Alexander MuiriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Rajeev DhuparORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 16, 2026

Integrative multi-omic analysis identifies tumor-intrinsic p38 as a driver of immune exclusion in human epithelial cancers

Rebekah Dadey, Krishna Beer Singh, Rose Doerfler…·Riyue Bao

This study identifies tumor-intrinsic p38 activation as a driver of immune exclusion in epithelial cancers and suggests it as a therapeutic target to overcome immunotherapy resistance.

DOI 10.64898/2026.06.11.731716

humanscRNA-seq

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ImmunologybioRxivPreprintMay 18, 2026

Microplastics inhibit macrophage bioenergetics impairing homeostatic function and immune responsiveness

Rajeev Dhupar, Hannah Mfonobong Udoh, Naila Noureen…·Adam C. Soloff

This study shows that microplastics impair macrophage bioenergetics and immune function, reducing antigen presentation and increasing disease susceptibility.

DOI 10.64898/2026.05.14.725255

mousehuman

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Cancer BiologybioRxivPreprintFeb 8, 2025

Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2ALow tumors via increased macrophage phagocytosis

Raquel Buj, Aidan R. Cole, Jeff Danielson…·Katherine M. Aird

This study shows that zinc availability in the tumor microenvironment affects anti-PD1 therapy response in CDKN2A-low tumors through macrophage phagocytosis.

3 citations

mouseproteomics

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