Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage
Rasha Q. Al‐Rahahleh, Wynand Paul Roos, Kate M. Saville, Joel Andrews, Zhijin J. Wu, Christopher A. Koczor, Aishwarya Prakash, Robert William Sobol
The paper evaluates WWE and macrodomain proteins as PAR probes in live cells and shows unique PAR dynamics that can modulate the DNA damage response.
DNA repair · May 21, 2025Peer-reviewedMolecular Biology