Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy
Susana G. Martins, Vanessa Ribeiro, Catarina Melo, Cláudia Paulino-Cavaco, Dario Antonini, Sharadha Dayalan Naidu, Fernanda Murtinheira, Inês T.E. Fonseca, Bérénice Saget, Mafalda Pita, Diogo R. Fernandes, Pedro Gameiro dos Santos, Gabriela Rodrigues, Rita Zilhão, Federico Herrera, , Sólveig Þorsteinsdóttir
This study investigates the early molecular changes in LAMA2-CMD using a mouse model, identifying gene expression, cytoskeletal, and DNA repair defects at disease onset.
Life Science Alliance · Oct 8, 2024Peer-reviewedDevelopmental Biology