Ana Rita Carlos

CD24 Acts as an Evolutionarily Conserved Innate Immune Checkpoint in Colorectal Cancer

This study identifies CD24 as an innate immune checkpoint in colorectal cancer that promotes tumor survival by inhibiting macrophage-mediated clearance, validated through zebrafish models and human data.

Biliverdin Reductase Catalytic Activity Is Essential for Malaria Resistance

This study shows that BVRA's catalytic activity is essential for malaria resistance and identifies a bilirubin concentration threshold needed for protection.

Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy

This study investigates the early molecular changes in LAMA2-CMD using a mouse model, identifying gene expression, cytoskeletal, and DNA repair defects at disease onset.