Pharmacology & ToxicologyJournal of Pharmacology and Experimental TherapeuticsPeer-reviewed
Relating GPCR domains with functionality: receptor helix-bundle and C-terminus differentially influence GRK-specific functions and β-arrestin-mediated regulation
Edda S. F. Matthees, Raphael Silvanus Haider, Laura Klement…·Carsten Hoffmann
The paper investigates how GPCR domains influence β-arrestin functions and conformational changes, revealing domain-specific effects on signaling outcomes.