Author

Raphael Silvanus Haider

University of NottinghamORCID 0000-0002-5924-6545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

Carsten HoffmanniD· 2 shared Arno Claßen· 1 shared Carla Ziegler· 1 shared Carsten BolmiD· 1 shared Edda S. F. MattheesiD· 1 shared Frank G. SchaapiD· 1 shared Gregory van der KroftiD· 1 shared Hans M.H. van EijkiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

Carsten HoffmannORCID

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2 papers

Recent·Most cited

Relating GPCR domains with functionality: receptor helix-bundle and C-terminus differentially influence GRK-specific functions and β-arrestin-mediated regulation

Edda S. F. Matthees, Raphael Silvanus Haider, Laura Klement, Mona Reichel, Nina Kathleen Blum, Verena Weitzel, Thimea Trüpschuch, Carla Ziegler, Julia Drube, Stefan Schulz, Carsten Hoffmann

The paper investigates how GPCR domains influence β-arrestin functions and conformational changes, revealing domain-specific effects on signaling outcomes.

Journal of Pharmacology and Experimental Therapeutics · Mar 1, 2025Peer-reviewedPharmacology & Toxicology

Microbially-conjugated Bile Salts Found in Human Bile Activate the Bile Salt Receptors TGR5 and FXR.

Ümran Ay, Martin Leníček, Raphael Silvanus Haider, Arno Claßen, Hans M.H. van Eijk, Kiran V.K. Koelfat, Gregory van der Kroft, Ulf P. Neumann, Carsten Hoffmann, Carsten Bolm, Steven W.M. Olde Damink, Frank G. Schaap

The paper identifies microbial bile salt conjugates that activate TGR5 and FXR receptors in human systems and quantifies their presence in blood and bile.

Hepatology Communications · Mar 22, 2024Peer-reviewedMolecular Biology