GeneticseLifePeer-reviewed
Uncharacterized yeast gene YBR238C, an effector of TORC1 signaling in a mitochondrial feedback loop, accelerates cellular aging via HAP4- and RMD9-dependent mechanisms
Mohammad Alfatah, Jolyn Jia Jia Lim, Yizhong Zhang…·Frank Eisenhaber
This study identifies YBR238C as a regulator of cellular aging in yeast, showing it modulates mitochondrial function through HAP4 and RMD9, and links TORC1 activity to mitochondrial feedback loops affecting aging.
8 citations