Trishia Yi Ning Cheng

The paper shows copper and iron regulate cellular survival through distinct TORC1 and AMPK pathways in yeast under nutrient stress.

The paper identifies metabolic state transitions regulated by TORC1 that influence cellular aging in yeast and human cells.

This study shows mitochondrial competence determines cellular responses to metabolic interventions during aging, with TORC1 signaling and mitochondrial function being key factors.

This study compares sixteen iPSC-CM differentiation protocols to identify how protocol-dependent cell states affect disease modeling capacity for cardiovascular conditions.

This study uses RNA-sequencing to analyze how calorie restriction and rapamycin affect gene expression in yeast, revealing their synergistic effect in extending postmitotic cell lifespan.

This study identifies YBR238C as a regulator of cellular aging in yeast, showing it modulates mitochondrial function through HAP4 and RMD9, and links TORC1 activity to mitochondrial feedback loops affecting aging.

This study identifies three distinct pathways by which glucose metabolism activates TORC1 in yeast, including both Rag GTPase-dependent and independent mechanisms.

This study identifies hemin as an anti-aging agent that extends cellular lifespan through the AMPK pathway and synergizes with rapamycin in human and yeast models.