Cell BiologybioRxivPreprint
Senataxin loss induces cGAS–STING-mediated mitochondrial dysfunction
Judith L.A. Fishburn, Hongchang Zhao, William Fosselman…·Jacqueline H. Barlow
This study shows that Senataxin loss leads to mitochondrial dysfunction via the cGAS-STING pathway in both mouse cells and AOA2 patient cells.