Protein-driven colloid-osmotic pressure controls nuclear size, organization, and function
Shin Ohsawa, Gloria Sáncho-Andrés, Guido Narduzzi, Wenshuo Zhao, Dhanashree Lakhe, Marianna E. Estrada, Abin Biswas, Hisashi Moriizumi, Evgeny A. Zatulovskiy, Simone Reber, Madhav Jagannathan, Gabriel E. Neurohr
The paper shows that protein-driven osmotic pressure regulates nuclear size and function, affecting chromatin organization and gene expression in yeast, human, and fly cells.
bioRxiv · Sep 7, 2026 · PreprintCell Biology