Abin Biswas

The physical state of the nucleus tracks its function across eukaryotes

The paper investigates the relationship between nuclear density and function across eukaryotes, finding that nuclear import, not transcription, determines density in some organisms.

Protein-driven colloid-osmotic pressure controls nuclear size, organization, and function

The paper shows that protein-driven osmotic pressure regulates nuclear size and function, affecting chromatin organization and gene expression in yeast, human, and fly cells.

Inhomogeneous Tau polymerization, core-shell organization, and seed formation during Tau condensate aging

This study shows how Tau condensates age into elastic networks with inhomogeneous polymerization and seed formation, providing mechanistic insight into their transition to pathological aggregates.

Cell State-Specific Cytoplasmic Material Properties Control Spindle Architecture and Scaling

The paper investigates how cytoplasmic density changes during cell differentiation and how this affects mitotic spindle architecture and scaling.

Hierarchical Heterogeneities in Spatiotemporal Dynamics of the Cytoplasm

This study uses differential dynamic microscopy to analyze cytoplasmic dynamics in Xenopus laevis egg extracts and HeLa cells, revealing subdiffusive motion and cytoskeletal influences on fluidity.

Mechanistic basis of temperature-adaptation in microtubule dynamics across frog species

This study investigates how temperature adaptation in microtubule dynamics is achieved through sequence changes in tubulin from three frog species.