Author

Markus Lubeck

Bruker (Germany)ORCID 0000-0002-9653-8096Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Approach:experimental assay· 3 Organism:multiple species· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Andreas‐David BrunneriD· 3 shared Florian MeieriD· 3 shared Matthias ManniD· 3 shared Oliver Raether· 3 shared Heiner Koch· 2 shared Jürgen CoxiD· 2 shared Melvin A. ParkiD· 2 shared Nicolai BacheiD· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Andreas‐David BrunnerORCID

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Author profile →

4 papers

Recent·Most cited

Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation

Andreas‐David Brunner, Marvin Thielert, Catherine G. Vasilopoulou, Constantin Ammar, Fabian Coscia, Andreas Mund, Ole B. Hørning, Nicolai Bache, Amalia Apalategui, Markus Lubeck, Sabrina Richter, David S. Fischer, Oliver Raether, Melvin A. Park, Florian Meier, , Matthias Mann

The paper develops a high-sensitivity mass spectrometry workflow to quantify single-cell proteome changes upon perturbation, revealing a stable core proteome despite transcriptomic variability.

Molecular Systems Biology · Feb 28, 2022Peer-reviewedSystems Biology

Parallel accumulation - serial fragmentation combined with data-independent acquisition (diaPASEF): Bottom-up proteomics with near optimal ion usage

Florian Meier, Andreas‐David Brunner, Max Frank, Annie Ha, Isabell Bludau, Eugenia Voytik, Stephanie Kaspar‐Schoenefeld, Markus Lubeck, Oliver Raether, Ruedi H. Aebersold, Ben C. Collins, Hannes Luc Röst, Matthias Mann

The paper introduces a new DIA scan mode that improves peptide precursor ion sampling and identification specificity using ion mobility, achieving high proteome coverage and accuracy.

bioRxiv · Mar 11, 2020 · PreprintSystems Biology

MaxQuant software for ion mobility enhanced shotgun proteomics

Nikita A. Prianichnikov, Heiner Koch, Scarlet Koch, Markus Lubeck, Raphael Heilig, Sven Brehmer, Román Fischer, Jürgen Cox

The paper introduces an enhanced MaxQuant software for ion mobility shotgun proteomics, improving quantification accuracy and coverage using 4D data analysis.

Molecular & Cellular Proteomics · Mar 10, 2020Peer-reviewedBioinformatics

Online parallel accumulation - serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer

Florian Meier, Andreas‐David Brunner, Scarlet Koch, Heiner Koch, Markus Lubeck, Michael Krause, Niels Goedecke, Jens Decker, Thomas Kosinski, Melvin A. Park, Nicolai Bache, Ole B. Hørning, Jürgen Cox, Oliver Raether, Matthias Mann

The paper introduces the timsTOF Pro instrument with online PASEF, achieving high sensitivity and reproducibility in proteomics.

Molecular & Cellular Proteomics · Nov 5, 2018Peer-reviewedSystems Biology