Catherine G. Vasilopoulou

Detecting Differential Alternative Splicing in Mass Spectrometry-based Proteomics Data

The paper introduces MS-EmpiReS, a method to detect differential alternative splicing in proteomics data, identifying cancer-relevant splicing candidates and showing correlation with RNA sequencing.

McIdas localizes at centrioles and controls centriole numbers through PLK4-dependent phosphorylation

This study identifies McIdas as a regulator of centriole numbers through PLK4-dependent phosphorylation, linking its role in cell cycle control to centriole duplication.

Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation

The paper develops a high-sensitivity mass spectrometry workflow to quantify single-cell proteome changes upon perturbation, revealing a stable core proteome despite transcriptomic variability.

Trapped ion mobility spectrometry (TIMS) and parallel accumulation - serial fragmentation (PASEF) enable in-depth lipidomics from minimal sample amounts

This paper develops a high-sensitivity lipidomics workflow using TIMS and PASEF, enabling deeper lipid analysis from minimal samples with improved speed and coverage.