A prototype timsOmni platform enables confident annotation of key hypervariable regions of IgG immunoglobulins using low- and high-energy electron-based fragmentation.
Simon Ollivier, Dina Schuster, Danique M.H. van Rijswijck, Iuliia Stroganova, Athanasios Smyrnakis, Jan Fiala, Mariangela Kosmopoulou, Detlev Suckau, Stuart Pengelley, Oliver Raether, Jean‐François Greisch, Dimitris K Papanastasiou, Albert J. R. Heck
bioRxiv · Oct 29, 2025 · PreprintBiochemistry