PTPRS is a novel marker for early tau pathology and synaptic integrity in Alzheimer's disease
Alexandre Poirier, Cynthia Picard, Anne Labonté, Isabelle Aubry, Daniel S. Auld, Henrik Zetterberg, Kaj Blennow, Judes Poirier, John C.S. Breitner, Justin Miron, Sylvia Villeneuve, R. Nathan Spreng, Pedro Rosa‐Neto, Jennifer Tremblay‐Mercier, Michel L. Tremblay
The paper identifies PTPRS as a neuroprotective marker in Alzheimer's disease, showing associations with reduced tau pathology and synaptic degeneration, particularly in males.
Scientific Reports · Jun 26, 2024Peer-reviewedNeuroscience