Arunkumar Krishnan

Expanding the Landscape of BREX Diversity: Uncovering Multi-Layered Functional Frameworks and Identification of Novel BREX-Related Defense Systems

The paper expands the BREX diversity by identifying new BR systems and a composite anti-invader system, revealing a multi-layered functional framework for defense mechanisms.

Amphibious Transitions Drive Lineage-Specific Diversification of Olfactory Receptors in Vertebrates

This study examines olfactory receptor (OR) evolution in amphibious vertebrates, finding that OR repertoire expansion is most pronounced in these species due to ecological pressures and sensory trade-offs.

Genome of the Predatory Volute Melo melo Provides Insights into Adaptive Gene Family Diversification in a Basal Neogastropod Lineage

This study presents the first high-contiguity genome of Melo melo, revealing gene family expansions linked to its predatory lifestyle and ecological adaptation.

Uncovering the Structural and Functional Implications of Uncharacterized NSPs and Variations in the Molecular Toolkit Across Mammalian and Non-Mammalian Arteriviruses

This study identifies uncharacterized NSPs and variations in molecular toolkits across mammalian and non-mammalian arteriviruses using comparative genomics and sequence-structure analysis.

Evolutionary Dynamics of Lineage-Specific Class-A GPCR Subsets Reveal Widespread Chemosensory Roles and Adaptations in Lophotrochozoa

The paper identifies lineage-specific expansions of Class-A GPCRs in Lophotrochozoa, linking them to habitat adaptations and chemosensory functions.

A ubiquitin-based mechanism for the oligogenic inheritance of heterotaxy and heart defects

This study identifies a ubiquitin-based genetic mechanism linking Megf8 and Mgrn1 mutations to congenital heart defects and heterotaxy through altered Hedgehog signaling.

The unexpected provenance of components in eukaryotic nucleotide-excision-repair and kinetoplast DNA-dynamics from bacterial mobile elements

The paper identifies the bacterial origin of DNA repair and kinetoplast DNA components in eukaryotes through computational analysis of protein domains.