Luke P. Lee

This paper introduces a chirality-driven photonic PCR method that enables rapid, label-free genetic amplification by using chiral plasmonic nanoparticles to enhance photothermal conversion and DNA synthesis efficiency.

This paper develops a continuous regenerative peritoneal dialysis system using cascaded nano-ring dialyzers, achieving toxin removal in a canine model.

The paper identifies disease-prone states in human mesocortical assembloids using multimodal profiling, revealing intrinsic susceptibility to neurodegeneration.

EVscope is a bioinformatics pipeline for analyzing EV RNA-seq data, improving read assignment and contamination correction with a comprehensive annotation and visualization tool.

This paper presents an OECT-based sensor for rapid, sensitive detection of extracellular vesicles in Alzheimer's disease, showing improved sensitivity and reduced detection time.

This paper introduces a human kidney epithelial microphysiological platform (Epi-MAP) to model collecting duct physiology from stem cells, enabling advanced functional analysis and drug testing.

This paper introduces a dynamic kidney organoid microphysiological analysis platform to improve reproducibility, accuracy, and utility in kidney research and drug development.

This paper introduces a microphysiological platform for long-term monitoring of midbrain organoids, capturing electrophysiological development and modeling Parkinson's disease-like alterations.

This study investigates extracellular vesicles in urban water systems to link human activities with microbial community impacts on public health and river biodiversity.