The paper develops XCiMS software to analyze LC-IMS-MS data and evaluates how ion mobility spectrometry improves untargeted metabolomics by reducing chimeric spectra and providing CCS values.

bioRxiv · Oct 26, 2026 · PreprintBioinformatics

Maternal PFAS Transfer through Lactation: Dolphin Milk Reveals Routes of Early-Life Exposure

Kara M. Joseph, Ashlee T. Falls, Sarah J. Rehm, James N. Dodds, Weihsueh A. Chiu, Michael L. Power, Erin Shammel Baker

This study analyzes PFAS concentrations in dolphin milk over two years, finding high levels of PFOS exceeding safety thresholds and suggesting breastmilk as a major source of early-life PFAS exposure.

Analytical and Bioanalytical Chemistry · Feb 3, 2026Peer-reviewedBiochemistry

Unlocking the Bile Acid Universe: Advanced Workflows and a Multidimensional Library of 280 Unique Species

Guozhi Zhang, E. Vincent, Sadie M. Disselkoen, James N. Dodds, Quentin DuVal-Smith, Abubaker Patan, Ipsita Mohanty, Victoria Deleray, Jian Zhang, Paul A Thiessen, Evan Bolton, Emma Schymanski, Pieter C. Dorrestein, Casey M. Theriot, Erin Shammel Baker

The paper develops a multidimensional bile acid reference library and evaluates workflows for accurate bile acid measurement in biological samples.

Sustainable Microbiology · Jan 1, 2026Peer-reviewedMicrobiology

Reference Library for Suspect Non-targeted Screening of Environmental Toxicants Using Ion Mobility Spectrometry-Mass Spectrometry

Devin Teri, Noor A. Aly, James N. Dodds, Jian Zhang, Paul A Thiessen, Evan Bolton, Kara M. Joseph, Antony Williams, Emma Schymanski, Ivan Rusyn, Erin Shammel Baker

The paper creates a database of IMS-MS data for 4,685 xenobiotic chemicals to enable rapid suspect screening of environmental contaminants.

Communications Chemistry · Aug 1, 2025Peer-reviewedEcology