Vendula Horáčková

Kelch13 stochastics determine drug survival in resistant malaria parasites

The paper shows that stochastic variation in K13 protein levels determines drug survival in genetically identical malaria parasites, explaining why only some survive artemisinin treatment.

A bridge-like lipid transfer protein is critical for generation of invasive stages in malaria parasites

This study identifies PfVPS13L1 as a critical lipid transfer protein in malaria parasites that facilitates lipid transfer from the ER to the inner membrane complex, essential for schizogony.

Protein landscape of the chromatin states in the malaria parasite Plasmodium falciparum

The paper presents a proteomic characterization of chromatin states in Plasmodium falciparum using proximity-labelling approaches, identifying 214 proteins and validating new chromatin components and functions.