Saurabh Umrao

Programmable DNA Assemblies Reconstitute Supramolecular Protein Function

The paper introduces CASCAD, a DNA nanoplatform that reconstitutes supramolecular protein function, specifically apoptosome activity, through programmable assembly of caspase recruitment domains.

APIPred Web 1.0: A Web Platform to Predict Potential Aptamer Sequences for Protein targets

APIPred Web 1.0 predicts aptamer sequences for protein targets using machine learning and structural analysis, generating experimentally usable candidates with high specificity.

Broad-Spectrum HIV-1 Detection and Neutralization via Multivalent Designer DNA Nanostructures

This paper develops a DNA nanostructure platform for ultrasensitive HIV-1 detection and antiviral activity, showing improved binding affinity and diagnostic performance.

Hybrid peptide DNA nanomaterials enable potent and broad-spectrum virus neutralization

This paper develops hybrid peptide-DNA nanomaterials that neutralize influenza viruses more effectively than free peptides by enhancing multivalent binding and reducing toxicity.