Hybrid peptide DNA nanomaterials enable potent and broad-spectrum virus neutralization
Saurabh Umrao, Abhisek Dwivedy, Payton Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang
This paper develops hybrid peptide-DNA nanomaterials that neutralize influenza viruses more effectively than free peptides by enhancing multivalent binding and reducing toxicity.
bioRxiv · Jul 21, 2025 · PreprintBioengineering