Author
Dartmouth CollegeORCID 0000-0002-9745-8135Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Matthew D. Slein, Lesle M Jimenez, Iara M. Backes…·Margaret E. Ackerman
This study shows that gB-targeting antibodies protect neonatal mice from HSV infection, requiring both neutralization and Fc effector functions, with transgenerational protection achievable via AAV-mediated delivery.
Matthew D. Slein, Iara M. Backes, Lesle M Jimenez…·Margaret E. Ackerman
The study shows engineered antibodies lacking Fc receptor binding improve HSV protection, suggesting vaccine strategies targeting IgG3 could enhance immunity.
Abigail J. Dutton, C. D. Patel, S. A. Taylor…·David A. Leib
This study shows that asymptomatic neonatal HSV infection in mice causes long-term cognitive impairment, highlighting the role of the γ34.5 gene in neurovirulence.