Kevin Patrick Pipe

Myelinated mechano-nociceptors encode noxious cold and underlie hypersensitivity in pulpitis

This study identifies myelinated high threshold-mechanonociceptors as the neural basis for tooth cold sensitivity and shows their role in hypersensitivity during pulpitis.

Intradental mechano-nociceptors serve as sentinels that prevent tooth damage

This study identifies intradental high-threshold mechano-nociceptors that detect tooth damage, produce pain, and trigger protective reflexes.

A Spinal Circuit That Transmits Innocuous Cool Sensations

The paper identifies a spinal circuit that transmits innocuous cool sensations by characterizing a specific population of interneurons.