Author

Jayda Carroll-Deaton

Medical University of South CarolinaORCID 0000-0002-9831-3528Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

Michael D. ScofieldiD· 4 shared Annaka M. Westphal· 3 shared James M. OtisiD· 3 shared Lisa M. GreeniD· 3 shared Rachel E. ClarkeiD· 3 shared Adam R. DentoniD· 2 shared Bayleigh E. Pagoota· 2 shared Bogdan BordieanuiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersNeuroscience

Michael D. ScofieldORCID

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4 papers

Recent·Most cited

Cortical astrocytes flexibly encode reward contingencies and shape conditioned behavior

Jacqueline E. Paniccia, Roger I. Grant, Annaka M. Westphal, Rachel E. Clarke, Elizabeth M. Doncheck, Bayleigh E. Pagoota, Jayda Carroll-Deaton, Bogdan Bordieanu, Sophie Buchmaier, Lydia G. Klumb, Lisa M. Green, Joshua A. Boquiren, James M. Otis, Michael D. Scofield

This study shows prefrontal astrocytes encode reward contingencies and adapt to changes in reward associations, influencing conditioned behavior.

bioRxiv · Dec 11, 2025 · PreprintNeuroscience

Enhanced Fear Extinction Through Infralimbic Perineuronal Net Digestion: The Modulatory Role of Adolescent Alcohol Exposure

J. Daniel Obray, Adam R. Denton, Jayda Carroll-Deaton, Kristin Marquardt, L. Judson Chandler, Michael D. Scofield

This study shows that adolescent alcohol exposure alters perineuronal net (PNN) expression in the infralimbic cortex, reducing the effectiveness of PNN digestion to enhance fear extinction.

Alcohol · Mar 1, 2025Peer-reviewedNeuroscience

Corticostriatal ensemble dynamics across heroin self-administration to reinstatement

Rachel E. Clarke, Roger I. Grant, Shannon N. Woods, Bayleigh E. Pagoota, Sophie Buchmaier, Bogdan Bordieanu, Anna Tsyrulnikov, Annaka M. Westphal, Jacqueline E. Paniccia, Elizabeth M. Doncheck, Jayda Carroll-Deaton, Kelsey M. Vollmer, Amy L. Ward, Kion T. Winston, Danielle I. King, , James M. Otis

This study uses two-photon calcium imaging to analyze corticostriatal neuron activity in mice during heroin self-administration and relapse, identifying distinct neuronal ensembles and their role in drug-seeking behaviors.

bioRxiv · Jun 21, 2024 · PreprintNeuroscience

Accumbens Nitrergic Interneurons Drive the Cell Type-Specific Synaptic Plasticity Required for Cue-Induced Cocaine Seeking

Adam R. Denton, Rachel E. Clarke, Lisa M. Green, Jayda Carroll-Deaton, Annaka M. Westphal, Benjamin M. Siemsen, Ashley G. Brock, Elizabeth A. Hochberg, Jacob Lavine, Makoto Taniguchi, Jacqueline F. McGinty, Alexander C.W. Smith, Constanza García‐Keller, James M. Otis, Michael D. Scofield

This paper identifies nitrergic interneurons as key mediators of cue-induced synaptic plasticity in D1 MSNs required for cocaine seeking, showing that targeting nNOS or mGluR5 blocks relapse.

bioRxiv · Apr 5, 2024 · PreprintNeuroscience