Author

Jessica D. Sun

Reset TherapeuticsORCID 0000-0002-9844-9767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alex Laihsu· 2 shared Nikki KimuraiD· 2 shared Pamela SantiagoiD· 2 shared Paul S. HumphriesiD· 2 shared Ross Bersot· 2 shared Sarah W. Wurts· 2 shared Aayush GuptaiD· 1 shared Akihiro YamanakaiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersNeuroscience

Alex Laihsu

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3 papers

Recent·Most cited

Novel Interpretable Tissue-Specific and Multi-Tissue Transcriptomic Clocks to Infer Aging Mechanisms

Aayush Gupta, Mindren Lu, Jessica D. Sun

This paper develops tissue-specific and multi-tissue transcriptomic clocks using XGBoost to predict age and identify aging-related genes from GTEx data.

bioRxiv · May 11, 2021 · PreprintGenomics

Rapid, noninvasive, and unsupervised detection of sleep/wake using piezoelectric monitoring for pharmacological studies in narcoleptic mice

Sarah W. Wurts, Jessica D. Sun, Alex Laihsu, Nikki Kimura, Pamela Santiago, Kevin D. Donohue, Bruce F. O’Hara, Ross Bersot, Paul S. Humphries

This paper introduces PiezoSleep, a noninvasive method to detect sleep/wake in narcoleptic mice, showing it can identify phenotypes and screen drugs efficiently.

bioRxiv · Sep 25, 2018 · PreprintNeuroscience

Partial ablation of the orexin field induces a sub narcoleptic phenotype in a conditional mouse model of orexin neurodegeneration

Sarah W. Wurts, Jessica D. Sun, Pamela Santiago, Alex Laihsu, Nikki Kimura, Akihiro Yamanaka, Ross Bersot, Paul S. Humphries

This study shows that partial orexin neuron loss in mice leads to a sub-narcoleptic phenotype with compensatory wake-promotion, resembling narcolepsy type 2.

SLEEP · May 31, 2018Peer-reviewedNeuroscience