Author

Sarah W. Wurts

Reset Therapeutics

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Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

Alex Laihsu· 2 shared Jessica D. SuniD· 2 shared Nikki KimuraiD· 2 shared Pamela SantiagoiD· 2 shared Paul S. HumphriesiD· 2 shared Ross Bersot· 2 shared Akihiro YamanakaiD· 1 shared Bruce F. O’HaraiD· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 34 mutual co-author links

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2 shared papersNeuroscience

Alex Laihsu

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 25, 2018

Rapid, noninvasive, and unsupervised detection of sleep/wake using piezoelectric monitoring for pharmacological studies in narcoleptic mice

Sarah W. Wurts, Jessica D. Sun, Alex Laihsu…·Paul S. Humphries

This paper introduces PiezoSleep, a noninvasive method to detect sleep/wake in narcoleptic mice, showing it can identify phenotypes and screen drugs efficiently.

7 citations

mouseimaging

𝕏 PostBluesky

NeuroscienceSLEEPPeer-reviewedMay 31, 2018

Partial ablation of the orexin field induces a sub narcoleptic phenotype in a conditional mouse model of orexin neurodegeneration

Sarah W. Wurts, Jessica D. Sun, Pamela Santiago…·Paul S. Humphries

This study shows that partial orexin neuron loss in mice leads to a sub-narcoleptic phenotype with compensatory wake-promotion, resembling narcolepsy type 2.

13 citations

mouseexperimental assay

𝕏 PostBluesky