NeuroscienceNeurobiology of DiseasePeer-reviewed
Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity
Fanny L. Lemarié, Nicholas S. Caron, Shaun S. Sanders…·Michael R. Hayden
This study investigates the role of HTT palmitoylation in Huntington disease by assessing its dysregulation in models and showing that modulating palmitoylation reduces mHTT toxicity.