Author

Doğukan Mizrak

Columbia UniversityORCID 0000-0002-9885-9686Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

Alexandra L. JoyneriD· 2 shared Nermin Sumru BayiniD· 2 shared Peter A. SimsiD· 2 shared Alex PauliD· 1 shared Ana C. DelgadoiD· 1 shared Angel R. Maldonado‐SotoiD· 1 shared Aviv MadariD· 1 shared Benjamin F. CravattiD· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Alexandra L. JoynerORCID

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3 papers

Recent·Most cited

Release of stem cells from quiescence reveals multiple gliogenic domains in the adult brain

Ana C. Delgado, Angel R. Maldonado‐Soto, Violeta Silva-Vargas, Doğukan Mizrak, Thomas von Känel, Kelly R. Tan, Alex Paul, Aviv Madar, Henar Cuervo, Jan Kitajewski, Chyuan‐Sheng Lin, Fiona K. Doetsch

The paper identifies multiple gliogenic domains in the adult V-SVZ by studying PDGFRβ-expressing NSCs and their release from quiescence.

Science · Jun 10, 2021Peer-reviewedNeuroscience

ASCL1 drives induction of a transitory cell state required for repair of the injured neonatal brain

Nermin Sumru Bayin, Doğukan Mizrak, Daniel N. Stephen, Zhimin Lao, Peter A. Sims, Alexandra L. Joyner

The paper identifies a transitory cell state driven by ASCL1 that enables neural reprogramming in the injured neonatal brain.

bioRxiv · Nov 3, 2020 · PreprintDevelopmental Biology

Single-cell profiling and SCOPE-seq reveal the lineage dynamics of adult neurogenesis and NOTUM as a key V-SVZ regulator

Doğukan Mizrak, Nermin Sumru Bayin, Jinzhou Yuan, Zhouzerui Liu, Radu M. Suciu, Micah J. Niphakis, Nhi Ngo, Kenneth M. Lum, Benjamin F. Cravatt, Alexandra L. Joyner, Peter A. Sims

The paper uses scRNA-seq and SCOPE-seq to study adult neurogenesis, identifying NOTUM as a key regulator of V-SVZ NSC differentiation and neurogenesis.

Cell Reports · Jun 1, 2020Peer-reviewedNeuroscience