U1 snRNP regulates cancer cell migration and invasion
Jung‐Min Oh, Christopher C. Venters, Chao Di, Anna Maria Pinto, Lili Wan, Ihab Younis, Zhiqiang Cai, Chie Arai, Byung Ran So, Jingqi Duan, Gideon Dreyfuss
Moderate U1 snRNP inhibition raises cancer cell migration and invasion by up to 500% and shortens 3'UTRs in many genes, while U1 overexpression has the opposite effects.
Nature Communications · Jan 7, 2020Peer-reviewedMolecular Biology✦ In-depth digest