Ihab Younis

The paper identifies a novel mechanism where premature cleavage and polyadenylation of the minor intron in PTEN generates a functional lncRNA, PINC, which modulates cellular proliferation in breast cancer.

This paper develops a scalable method using all-trans-retinoic acid to generate mesenchymal stem cells and adipocytes from human pluripotent stem cells with enhanced differentiation potential.

Moderate U1 snRNP inhibition raises cancer cell migration and invasion by up to 500% and shortens 3'UTRs in many genes, while U1 overexpression has the opposite effects.