Victoria H. James

Neuronal extracellular vesicles regulate axon development in primary cortical neurons via local miR-99a targeting of HS3ST2

This study shows neuronal extracellular vesicles deliver miR-99a to axons, targeting HS3ST2 to regulate axon growth in mouse cortical neurons.

Hybrid Scaffolds Decouple Biochemical & Biophysical Regulation of Cell Phenotype

This paper introduces hybrid scaffolds that independently control biochemical and biophysical properties to study their effects on cell phenotype, showing enhanced breast cancer cell proliferation and invasion.

Detecting Mitochondrial Free Radicals with Quantum Sensors: From Organelles to a D. melanogaster Model of Neurodegeneration

This paper uses quantum sensors to detect free radicals in Drosophila Parkinson's model, distinguishing Pink1-deficient flies from controls by identifying unique radical signatures.

A New Approach to Monitoring Protein Transfer via Extracellular Vesicles

The paper develops a method to track protein transfer via extracellular vesicles using SILAC and mass spectrometry, achieving 62% labeling efficiency but finding no correlation between EV concentration and protein uptake.

Multi-omic temporal landscape of plasma and synovial fluid-derived extracellular vesicles using an experimental model of equine osteoarthritis

The paper profiles extracellular vesicle cargo in plasma and synovial fluid of an equine osteoarthritis model using multi-omic approaches and identifies time-dependent changes in protein and RNA content.

Temporal Extracellular Vesicle Protein Changes following Intraarticular Treatment with Integrin α10β1-selected Mesenchymal Stem Cells in Equine Osteoarthritis

This study quantifies changes in synovial fluid extracellular vesicle proteomes after MSC treatment in equine osteoarthritis, identifying differentially expressed proteins and enriched pathways.

Small non-coding RNA landscape of extracellular vesicles from a post-traumatic model of equine osteoarthritis

The paper identifies small non-coding RNA biomarkers in extracellular vesicles from equine osteoarthritis models using small RNA sequencing and bioinformatics analysis.

Optical photothermal infrared spectroscopy can differentiate equine osteoarthritic plasma extracellular vesicles from healthy controls