Tim J. M. Welting

The paper profiles extracellular vesicle cargo in plasma and synovial fluid of an equine osteoarthritis model using multi-omic approaches and identifies time-dependent changes in protein and RNA content.

This study combines in silico and in vitro approaches to identify drug targets for osteoarthritis by modeling chondrocyte phenotype transitions and validating predictions in cell lines.

This study identifies differentially expressed small non-coding RNAs in equine synovial fluid associated with early osteoarthritis and links them to biological processes involved in disease pathogenesis.

This study identifies age-related changes in small non-coding RNA expression in equine chondrocytes and links them to cartilage and osteoarthritis pathways.

This study identifies snoRNA expression changes in cartilage ageing and osteoarthritis, showing their impact on chondrogenic and hypertrophic gene expression.