Mandy Jayne Peffers

The paper develops a low-annotation-budget classifier using active learning and PubMedBERT to identify chondrogenesis regulators from PubMed abstracts, achieving high performance with fewer annotations.

This study investigates how age and sex affect mRNA stability and polyadenylation in equine joint tissues, revealing sex-specific differences in transcript stability and age-related changes in polyadenylation site usage.

This study stratifies equine osteoarthritis using metabolomic and proteomic profiles of synovial fluid and identifies markers for OA severity.

The paper develops a method to track protein transfer via extracellular vesicles using SILAC and mass spectrometry, achieving 62% labeling efficiency but finding no correlation between EV concentration and protein uptake.

This study identifies a putative Jouvence snoRNA gene in the horse genome and finds its expression increases in ageing equine cartilage.

This study identifies metabolomic biomarkers of meniscal injury in dogs with cranial cruciate ligament disease using 1H NMR spectroscopy of synovial fluid.

The paper profiles extracellular vesicle cargo in plasma and synovial fluid of an equine osteoarthritis model using multi-omic approaches and identifies time-dependent changes in protein and RNA content.

This study characterizes polyadenylation patterns in human articular chondrocytes from healthy and osteoarthritic samples, finding limited polyA site changes in osteoarthritis compared to cancer.

This study quantifies changes in synovial fluid extracellular vesicle proteomes after MSC treatment in equine osteoarthritis, identifying differentially expressed proteins and enriched pathways.

The paper identifies small non-coding RNA biomarkers in extracellular vesicles from equine osteoarthritis models using small RNA sequencing and bioinformatics analysis.

The paper uses small-RNA sequencing to identify altered microRNA and snoRNA signatures in skeletal muscle of male mouse offspring from dams with low protein diets during lactation.

This study identifies differentially expressed small non-coding RNAs in equine synovial fluid associated with early osteoarthritis and links them to biological processes involved in disease pathogenesis.

This study identifies age-related changes in small non-coding RNA expression in equine chondrocytes and links them to cartilage and osteoarthritis pathways.

This study identifies snoRNA expression changes in cartilage ageing and osteoarthritis, showing their impact on chondrogenic and hypertrophic gene expression.