Nuclear polysaccharides maintain H3K9me3-heterochromatin and genomic stability
Xiuxiao Tang, Ranran Dai, Qi Li, Zhida Zhang, Hongmei Li, Lizi Lu, Hancheng Lin, Danling Ji, Wei Dan, Yuqi He, Xinyi Liu, Tao Yang, Wakam Chang, Yang Mao, Shisheng Sun, Junjun Ding
The paper shows that nuclear N-glycans modify INM proteins, regulate H3K9me3, and maintain genomic stability by interacting with SETDB1.
Nature Cell Biology · Apr 28, 2026Peer-reviewedMolecular Biology