Abraham Stijn Meijnikman

scOmnom: scalable end-to-end single-cell RNA-seq analysis with auditable resolution selection

scOmnom provides a scalable, semi-automated workflow for single-cell RNA-seq analysis, enabling auditable clustering-resolution selection and annotation refinement across large datasets.

Sex-stratified adipose-liver circuits in human MASLD

This study identifies sex-specific transcriptional differences in liver and visceral adipose tissue in MASLD and shows coordinated cross-tissue states.

Adipose Tissue Inflammation, Oxidative Stress, and Altered Adipogenesis Are Drivers of Dyslipidemia - A Multi-Omics Overview of Dyslipidemia in Obesity

This study investigates the role of adipose tissue in dyslipidemia through multi-omics analysis of patients with obesity, identifying inflammation, oxidative stress, and altered adipogenesis as key drivers.

Gut-derived bacterial flagellin induces beta-cell inflammation and dysfunction

This study shows that gut-derived bacterial flagellin contributes to beta-cell inflammation and dysfunction in type 2 diabetes.

Systems analysis of metabolic responses to a mixed meal test in an obese cohort reveals links between tissue metabolism and the gut microbiota

The paper analyzes metabolic responses to a mixed meal test in an obese cohort, linking tissue metabolism with gut microbiota changes and identifying potential biomarkers for T2DM.