Author

Drosos E. Karageorgopoulos

Oxford University Hospitals NHS TrustORCID 0000-0002-9959-9978Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ann Sarah WalkeriD· 2 shared Matthew ColpusiD· 2 shared Nicole E StoesseriD· 2 shared Sarah J OakleyiD· 2 shared Aysha Roohi· 1 shared Bernadette YoungiD· 1 shared Carlos RedingiD· 1 shared David W. EyreiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Ann Sarah WalkerORCID

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Author profile →

2 papers

Recent·Most cited

OxBreaker: species-agnostic pipeline for the analysis of outbreaks using nanopore sequencing

Carlos Reding, Katie M.V. Hopkins, Matthew Colpus, Nicholas D. Sanderson, Jessica Gentry, Sarah J Oakley, Mark Robin Campbell, Drosos E. Karageorgopoulos, Katie JM Jeffery, David W. Eyre, Philip Bejon, Nicole E Stoesser, Ann Sarah Walker, Bernadette Young

OxBreaker is a species-agnostic pipeline for analyzing bacterial and plasmid outbreaks using nanopore sequencing, offering high accuracy and accessibility for real-time genomic surveillance.

bioRxiv · Mar 19, 2026 · PreprintGenomics

E. coli phylogeny drives co-amoxiclav resistance through variable expression of blaTEM-1

William Matlock, Gillian Rodger, Emma Pritchard, Matthew Colpus, Natalia Kapel, Lucinda K. Barrett, Marcus R. Morgan, Sarah J Oakley, Katie L. Hopkins, Aysha Roohi, Drosos E. Karageorgopoulos, Matthew B. Avison, Ann Sarah Walker, Samuel Lipworth, Nicole E Stoesser

The paper shows that E. coli phylogeny influences blaTEM-1 expression and co-amoxiclav resistance through lineage-specific regulatory differences.

Nature Communications · Sep 30, 2025Peer-reviewedMicrobiology