Youngjun Park

Modulation of the RNAse P/MRP complex and mitochondrial ribosome enhances cytosolic ribosome coordination and sustains longevity

This study shows that restoring ribosomal homeostasis by targeting RNAse P/MRP or mitochondrial ribosome extends lifespan in C. elegans by improving proteostasis and ribosome assembly.

Effect of Data Heterogeneity in Clinical MALDI-TOF Mass Spectra Profiles on Direct Antimicrobial Resistance Prediction through Machine Learning

The paper introduces a large mass spectra dataset for antimicrobial resistance prediction, evaluates its performance, and analyzes the impact of data heterogeneity on machine learning models.

On the importance of data transformation for data integration in single-cell RNA sequencing analysis

This study evaluates the impact of data transformation methods on single-cell RNA sequencing integration and shows that optimized preprocessing can reduce batch effects and noise.

Species-Agnostic Transfer Learning for Cross-species Transcriptomics Data Integration without Gene Orthology

This paper develops a species-agnostic transfer learning method for cross-species transcriptomics data integration without gene orthology, showing improved performance in predicting unseen cell types.

Transfer Learning Compensates Limited Data, Batch-Effects, And Technical Heterogeneity In Single-Cell Sequencing

This paper demonstrates that transfer learning improves analysis of small single-cell datasets by overcoming data scarcity, batch effects, and technical heterogeneity using large-scale bulk data.