Author

Jennifer E. Jones

University of PittsburghORCID 0000-0002-9970-1063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Megan Culler FreemaniD· 3 shared Gal YoveliD· 2 shared Sarah Maya· 2 shared Isabella E. Bosco· 1 shared Jennifer L. Konopka‐AnstadtiD· 1 shared Jessica Ciomperlik-PattoniD· 1 shared Jessica E. PackardiD· 1 shared Jie LaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

Megan Culler FreemanORCID

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3 papers

Recent·Most cited

Enterovirus D68 VP1 and VP3 determine neurotropism in human spinal cord organoids

Jessica E. Packard, Jennifer E. Jones, Gal Yovel, Megan Culler Freeman

The paper investigates how mutations in EV-D68's VP1 and VP3 proteins affect neurotropism in human spinal cord organoids and links these findings to reduced neurovirulence observed after 2018.

Viruses · May 28, 2026Peer-reviewedMicrobiology

Recombinant B3 clade enterovirus D68 strains are efficiently rescued in 293T cells and infect human spinal cord organoids.

Jennifer E. Jones, Sarah Maya, Gal Yovel, Jessica Ciomperlik-Patton, Jennifer L. Konopka‐Anstadt, Megan Culler Freeman

This study develops a method to rescue B3 clade EV-D68 strains and shows they replicate more efficiently in spinal cord organoids than a neurovirulent B2 clade strain.

Journal of Virology · Apr 27, 2026Peer-reviewedMicrobiology

Immune cells promote paralytic disease in mice infected with enterovirus D68

Mikal A. Woods Acevedo, Jie Lan, Sarah Maya, Jennifer E. Jones, Isabella E. Bosco, John V. Williams, Megan Culler Freeman, Terence S. Dermody

This study shows that immune cell infiltration into the spinal cord promotes paralysis in mice infected with EV-D68, suggesting immune cell targeting as a therapeutic strategy.

Journal of Clinical Investigation · Jun 3, 2025Peer-reviewedMicrobiology