Eus J.W. Van Someren

REM Sleep Iota Oscillations Across the Lifespan

This study examines iota oscillations in REM sleep across age groups, finding age-related changes in frequency, amplitude, and bandwidth, with high heritability for most properties.

Active Bed Microclimate Regulation Modulates Sleep Architecture, Autonomic, and Central Nervous System Activity during Sleep

This study shows that active bed temperature regulation affects sleep depth, autonomic activity, and EEG patterns, with varying effects depending on cooling or heating settings.

Shared predicted effector genes of insomnia, anxiety and depression implicate synaptic processes as transdiagnostic drug targets

This study identifies shared genetic factors between insomnia, depression, and anxiety, highlighting synaptic processes as potential drug targets.

Modelling of brain dynamics reveals reduced switching between brain states in insomnia disorder - a resting state fMRI study

Multimodal brain imaging of insomnia, depression and anxiety symptoms: transdiagnostic commonalities and differences

This study uses multimodal brain imaging data from UK Biobank participants to identify shared and distinct brain properties associated with insomnia, depression, and anxiety symptoms.

Insomnia subtypes have differentiating deviations in brain structural connectivity

The paper identifies distinct structural brain connectivity deviations in insomnia subtypes using MRI data from multiple studies.

Reduced structural connectivity in Insomnia Disorder

This study identifies reduced structural connectivity in Insomnia Disorder using whole-brain network analysis, highlighting left insula and fronto-subcortical connections as key features.

Genome-wide Analysis of Insomnia (N=1,331,010) Identifies Novel Loci and Functional Pathways

This study identifies 202 genome-wide significant loci for insomnia using a large sample, linking them to specific brain cell types and pathways.