Indra Adrianto

The paper identifies cell type-specific gene expression and immune cell associations in keloid tissue using bulk RNA-Seq and single sample gene set enrichment analysis.

The paper identifies five SNPs in the DDX6-CXCR5 locus associated with autoimmune diseases and shows their functional effects on gene regulation in immune and epithelial cells.

HS-OmicsDB aggregates bulk and single-cell RNA sequencing data from untreated HS patients to profile gene expression in specific tissue types and map cell-specific gene expression in HS lesions.

The paper analyzes de novo mutations in 1,465 genomes to show similar mutation rates across ancestries but reduced rates in the Amish population, with environmental factors possibly influencing mutation rates.