Brianna L. Hill

Phendione, a T2R5 agonist, reduces cell viability and induces apoptosis in HNSCC cells and tumor samples, with T2R5 expression linked to better survival in HNSCC.

This study shows quercetin activates T2R14 in HNSCC cells, causing calcium responses, reduced viability, and mitochondrial depolarization.

This study shows bitter taste receptor agonists induce apoptosis in papillary thyroid cancer cells and higher TAS2R14 expression correlates with better patient survival.