Author

Zoey A. Miller

University of PennsylvaniaORCID 0000-0002-1955-4033Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Physiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Robert J. LeeiD· 5 shared Ryan M. CareyiD· 5 shared Joel C. Thompson· 3 shared Sarah M. SywanycziD· 3 shared April ParkiD· 2 shared Arielle Mueller· 2 shared Brianna L. HilliD· 2 shared Gavin TurneriD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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5 shared papersCancer Biology

Robert J. LeeORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TAS2R10 Suppresses ABCG2 Transporter-Associated Chemoresistance and Enhances Cisplatin Sensitivity in Head and Neck Squamous Cell Carcinoma

Lily Huang, Sarah M. Sywanycz, Priyanka Sahu, Leilei Hao, Kyle Polen, Gavin Turner, Zoey A. Miller, Robert J. Lee, Ryan M. Carey

This study shows caffeine enhances cisplatin sensitivity in HNSCC by increasing TAS2R10 expression and reducing ABCG2 expression.

bioRxiv · Jul 27, 2026 · PreprintCancer Biology

Pseudomonas aeruginosa metabolite 3-oxo-C12HSL induces apoptosis through T2R14 and the mitochondrial calcium uniporter

Zoey A. Miller, Arielle Mueller, Joel C. Thompson, Jordan S. Williams, April Park, Nabil F. Darwich, Yobouet Inès Kouakou, Sarah M. Sywanycz, B. Buchler, Nithin D. Adappa, James N. Palmer, Noam A. Cohen, Ryan M. Carey, Robert J. Lee

This study shows that 3-oxo-C12HSL from Pseudomonas aeruginosa induces apoptosis in HNSCC cells via T2R14 and mitochondrial calcium uniporter.

Cell Calcium · May 5, 2026Peer-reviewedPhysiology

Effects of Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine on intracellular calcium, mitochondrial function, and viability in human nasal epithelial cells

Joel C. Thompson, April Park, Yobouet Inès Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee

This study investigates the effects of pyocyanin and 1-hydroxyphenazine on calcium signaling, mitochondrial function, and cell viability in nasal epithelial cells and cancer cell lines.

International Forum of Allergy & Rhinology · Dec 19, 2025Peer-reviewedPhysiology

T2R5 agonist phendione decreases cell viability and induces apoptosis in head and neck squamous cell carcinoma

Sarah M. Sywanycz, Brianna L. Hill, Zoey A. Miller, Gavin Turner, Lily Huang, Kyle Polen, Robert J. Lee, Ryan M. Carey

Phendione, a T2R5 agonist, reduces cell viability and induces apoptosis in HNSCC cells and tumor samples, with T2R5 expression linked to better survival in HNSCC.

Molecular Cancer Therapeutics · Nov 7, 2025Peer-reviewedCancer Biology

Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer

Kimberly Wei, Brianna L. Hill, Joel C. Thompson, Zoey A. Miller, Arielle Mueller, Robert J. Lee, Ryan M. Carey

This study shows bitter taste receptor agonists induce apoptosis in papillary thyroid cancer cells and higher TAS2R14 expression correlates with better patient survival.

Head & Neck · Mar 5, 2025Peer-reviewedCancer Biology