Author

Lokesh Sharma

Yale UniversityORCID 0000-0002-9979-1900Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alicia N. RizzoiD· 1 shared Amy Zhao· 1 shared Anchen QiuiD· 1 shared Charles S Dela Cruz· 1 shared Edward Manning· 1 shared Faraaz Shah· 1 shared Gagan Heda· 1 shared Georgios D. KitsiosiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alicia N. RizzoORCID

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1 paper

Recent·Most cited

A Time-Resolved Single-Cell Atlas Reveals Infection-Status, Age-, and Sex-Dependent Immune Responses Drive Viral Disease Severity

Lujia Chen, Anchen Qiu, JooYoung Kim, Nebal Abu Hussein, Mengyao Lu, Karen Agaronyan, Kexin Sun, Yifan Yuan, Amy Zhao, Gagan Heda, Xinghua Lu, Georgios D. Kitsios, Alicia N. Rizzo, William Bain, Toru Nyunoya, , Lokesh Sharma

This study uses time-resolved single-cell RNA sequencing in mice to show age and sex influence immune responses and viral disease severity through altered gene expression and inflammation.

bioRxiv · Aug 11, 2026 · PreprintImmunology