William Bain

This study uses time-resolved single-cell RNA sequencing in mice to show age and sex influence immune responses and viral disease severity through altered gene expression and inflammation.

This study compares the pathogenic potential of classical and hypervirulent K. pneumoniae strains producing the K2 capsule, revealing differences in tissue tropism and mucoidy despite similar capsule production.

This study shows that TLR9 sensing of tissue damage during influenza infection promotes inflammation and antiviral responses, but its absence leads to impaired viral clearance and prolonged lung injury.